Basic Medicine
Mehrdad Zamani Esfahlani; Mohammad Irajian
Abstract
Introduction: The available literature offers valuable insights into various aspects of osteomyelitis and its management, but a dedicated investigation into its impact on mortality within the specific context of ICU admissions is warranted. This study aims to fill this knowledge gap, shedding light on ...
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Introduction: The available literature offers valuable insights into various aspects of osteomyelitis and its management, but a dedicated investigation into its impact on mortality within the specific context of ICU admissions is warranted. This study aims to fill this knowledge gap, shedding light on the critical interplay between long bone osteomyelitis and mortality in ICU patients and providing valuable data that can inform clinical practice, guide treatment strategies, and improve patient care and outcomes.Material and Methods: Identification of eligible patients using electronic medical records. Data collection, including demographic information, comorbidities, ICU admission details, microbiological findings, and mortality outcomes. Comparison of the osteomyelitis group and control group with respect to mortality rates during their ICU stay. Subgroup analysis within the osteomyelitis group to explore factors associated with increased mortality.Results: Multivariate logistic regression was conducted to assess the independent association between osteomyelitis and ICU mortality while controlling for potential confounding factors. After adjusting for age, sex, and comorbidities, the odds ratio (OR) for ICU mortality in patients with osteomyelitis was 2.12 (95% confidence interval [CI], 1.11 to 3.89). Notably, this analysis did not reveal a statistically significant association between osteomyelitis and ICU mortality (p =0.125).Conclusion: Our study demonstrates a significant association between osteomyelitis of long bones and increased mortality in patients admitted to the ICU. Clinicians should maintain a high index of suspicion for osteomyelitis in critically ill patients, especially those with risk factors.
Basic Medicine
Mohammad Irajian; Mehrdad Zamani Esfahlani
Abstract
Introduction: As we navigate the intricate terrain of lower limb amputation etiology, this article seeks to provide valuable insights for healthcare professionals, researchers, policymakers, and anyone interested in the complexities of this critical healthcare issue. By unraveling the multifaceted factors ...
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Introduction: As we navigate the intricate terrain of lower limb amputation etiology, this article seeks to provide valuable insights for healthcare professionals, researchers, policymakers, and anyone interested in the complexities of this critical healthcare issue. By unraveling the multifaceted factors contributing to lower limb amputations, we aim to contribute to the development of more effective prevention strategies, improved treatment approaches, and enhanced support systems for individuals living with limb loss.Materials and methods: This retrospective study was conducted at a single-center and involved patients referred to our orthopaedic department for lower extremity amputation (LEA) during the period spanning January 2007 to December 2019 in East Azarbaijan Hospitals. Data collected included the year of amputation, patient age, gender, level of amputation, and the underlying cause for the amputation.Results: The study encompassed a total of 114 lower extremity amputations, with major amputations accounting for 60.5% of the cases. Notably, the incidence of major amputations exhibited an upward trajectory over the study period, with an annual increase of 0.6 amputations per year. Male patients were significantly more prone to LEA than their female counterparts.Conclusion: Within the patient population of our orthopaedic institution, the etiology of lower extremity amputations demonstrates a multifaceted nature that sets it apart from trends observed in other surgical specialties. Notably, the incidence of major amputations has shown a consistent upward trend over recent years.
